What is Pulmozyme?

Pulmozyme^®(dornase alfa) is indicated for the management of cystic fibrosis patients with a forced vital capacity (FVC) of greater than 40% of predicted and over 5 years of age to improve pulmonary function.¹

Consider Pulmozymefor the management of cystic fibrosis.
An agent with a distinct mechanism of action in helping to clear mucus ^{1, 3-6}

Countries where Pulmozyme is approved

Pulmozyme is approved in > 65 countries. Please see the map below for further information.

Learn more

1. Pulmozyme SmPC, Electronic Medicines Compendium, accessed 10/8/18

3. Harms HK et al. Dnase International Study Group. Multicenter, open-label study of recombinant human Dnase in cystic fibrosis patients with moderate lung disease. Pediatr Pulmonol. 1998; 23(3): 155-161.

4. King, M. Mucolytics and mucus clearance. In Rubin BK, van der Sxhans CP, eds. Therapy for Mucus-Clearance Disorders. New Yoirk, NY: Marcel Dekker Inc, 2004:201-224.

5. Chmiel, JF, Kanstan MW. Anti-inflammatory medication for cystic fibrosis lung disease: selecting the most appropriate agent. Treat Respir Med. 2005; 4(4):255-273.

6. Puchelle E et al. Physical and functional properties of airway secretions in cystic fibrosis – therapeutic approaches. Respiration. 1995; 62(suppl 1) 2-12.

35. The Pharma Letter. EU gives go-ahead to Pulmozyme. https://www.thepharmaletter.com/article/eu-gives-go-ahead-to-pulmozyme. Accessed March 29, 2017

All Countries

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Argentina

Australia

Austria

Belarus

Belgium

Bolivarian Republic Of Venezuela

Bosnia and Herzegovina

Brazil

Bulgaria

Canada

Chile

Colombia

Costa Rica

Curaçao

Croatia

Cyprus

Czech Republic

Denmark

Dominican Republic

Ecuador

El Salvador

Estonia

Finland

France

Germany

Guatemala

Greece

Honduras

Hong Kong

Hungary

Ireland

Iceland

Israel

Italy

Jamaica

Japan

Kuwait

Latvia

Lebanon

Lithuania

Luxembourg

Macao

Macedonia

Malta

Mexico

Netherlands

New Zealand

Nicaragua

Norway

Oman

Panama

Paraguay

Peru

Poland

Portugal

Romania

Russian Federation

Serbia

Singapore

Slovakia

Slovenia

South Africa

Spain

Sweden

Switzerland

Trinidad and Tobago

Turkey

Ukraine

United Kingdom

United States

Uruguay

Argentina

http://www.roche.com.ar/

Local HCP Portal: https://www.dialogoroche.com/ar/home/sitios_de_productos/info_para_preescribir.html

Request Medical Information: https://medinfo.roche.com/

Australia

http://www.roche-australia.com/

Local HCP Portal: https://www.rocheinteract.com.au/medicine-and-resources/Pulmozyme.html

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Austria

https://www.roche.at

Local HCP Portal Pulmozyme content not available

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Belarus

http://www.roche.com

Local HCP Portal Pulmozyme content not available

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Belgium

http://www.roche.be

Local HCP Portal: https://www.rochepro.be/nl_be/wetenschappelijke-bijsluiters/pulmozyme.html

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Bolivarian Republic Of Venezuela

http://www.roche.com

Local HCP Portal Pulmozyme content not available

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Bosnia and Herzegovina

http://www.roche.com

Local HCP Portal Pulmozyme content not available

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Brazil

https://www.roche.com.br/

Local HCP Portal: https://www.dialogoroche.com/br/home/produtos/pulmozyme.html

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Bulgaria

http://www.roche.bg/

Local HCP Portal: https://www.rochemd.bg/bg_bg/products1/respiratory/pylmozyme.protected.html

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Canada

http://www.rochecanada.com/

Local HCP Portal : http://www.rochecanada.com/en/content/products_database/consumer-information/pulmozyme.html

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Chile

http://www.roche.cl/

Local HCP Portal: https://www.dialogoroche.com/mx/home/info_para_preescribir.html

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Colombia

http://www.roche.com.co/

Local HCP Portal: https://www.dialogoroche.com/mx/home/info_para_preescribir.html

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Costa Rica

http://www.roche-cac.com/

Local HCP Portal Pulmozyme content not available

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Curaçao

https://www.roche.com

Local HCP Portal Pulmozyme content not available

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Croatia

http://www.roche.hr

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Cyprus

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Czech Republic

http://www.roche.cz

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Denmark

http://www.roche.dk

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Dominican Republic

http://www.roche-cac.com/

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Ecuador

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El Salvador

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Estonia

https://www.roche.ee

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Finland

https://www.roche.fi

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France

http://www.roche.fr

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Germany

https://www.roche.de

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Guatemala

http://www.roche-cac.com/

Local HCP Portal Pulmozyme content not available

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Greece

http://www.roche.gr

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Honduras

http://www.roche-cac.com/

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Hong Kong

http://www.roche.com.hk

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Hungary

http://www.roche.hu/

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Ireland

https://www.roche.ie

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Iceland

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Israel

http://www.roche.co.il

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Italy

https://www.roche.it

Local HCP Portal: https://www.infomedics.it/it_it/products/pulmozyme.protected.html

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Jamaica

http://www.roche-cac.com/en

Local HCP Portal Pulmozyme content not available

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Japan

https://www.chugai-pharm.co.jp

Local HCP Portal Pulmozyme content not available

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Kuwait

http://www.roche-middleeast.com/

Local HCP Portal Pulmozyme content not available

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Latvia

http://www.roche.lv

Local HCP Portal Pulmozyme content not available

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Lebanon

http://www.roche-middleeast.com/

Local HCP Portal Pulmozyme content not available

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Lithuania

https://www.roche.lt/

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Luxembourg

https://www.roche.com/

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Macao

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Local HCP Portal Pulmozyme content not available

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Macedonia

http://www.roche.mk/

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Malta

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Mexico

https://www.roche.com.mx/

Local HCP Portal: https://www.dialogoroche.com/mx/home/info_para_preescribir.html

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Netherlands

This website is not intended for Dutch healthcare professionals. For further information, please visit: https://www.roche.nl

Local HCP Portal Pulmozyme content not available

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New Zealand

https://www.roche.co.nz/

Local HCP Portal Pulmozyme content not available

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Nicaragua

http://www.roche-cac.com/

Local HCP Portal Pulmozyme content not available

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Norway

https://www.roche.no

Local HCP Portal Pulmozyme content not available

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Oman

http://www.roche-middleeast.com/

Local HCP Portal Pulmozyme content not available

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Panama

http://www.roche-cac.com/

Local HCP Portal Pulmozyme content not available

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Paraguay

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Peru

https://www.roche.com.pe/

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Poland

https://www.roche.pl

Local HCP Portal Pulmozyme content not available

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Portugal

https://www.roche.pt

Local HCP Portal: https://www.rochenet.pt/pt_pt/medicamentos-roche/lista-de-medicamentos-roche/pulmozyme-alfa-dornase.protected.html

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Romania

https://www.roche.ro

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Russian Federation

https://www.roche.ru/

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Serbia

https://www.rochesrbija.rs/

Local HCP Portal Pulmozyme content not available

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Singapore

https://www.roche.com.sg

Local HCP Portal Pulmozyme content not available

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Slovakia

https://www.roche.sk

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Slovenia

https://www.roche.si

Local HCP Portal Pulmozyme content not available

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South Africa

https://www.roche.co.za/

Local HCP Portal Pulmozyme content not available

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Spain

https://www.roche.es

Local HCP Portal Pulmozyme content not available

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Sweden

https://www.roche.se

Local HCP Portal Pulmozyme content not available

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Switzerland

https://www.roche.ch

Local HCP Portal: www.roche-online.ch/de_ch/ppmsselfdetail.html#home

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Trinidad and Tobago

http://www.roche-cac.com/

Local HCP Portal Pulmozyme content not available

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Turkey

http://www.roche.com.tr

Local HCP Portal: https://www.medikaynak.com/u/pulmozyme

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Ukraine

https://www.roche.ua/

Local HCP Portal Pulmozyme content not available

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United Kingdom

https://www.roche.co.uk/

Local HCP Portal Pulmozyme content not available

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United States

https://www.gene.com/

Local HCP Portal Pulmozyme content : https://www.pulmozyme.com/

Request Medical Information: https://www.gene.com/contact-us/submit-medical-inquiry

Uruguay

https://www.roche.com.uy/

Local HCP Portal Pulmozyme content not available

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